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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'edfd3776e519e8ab09c8f583ccf2407ef4c1ec59811cee43af9a8b157f14f9ed' 
  AND token = 'z72FtPb0yeOhNL/pILi3mR+VwfQUtuNo5QYMoQmDVYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}