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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'af27c6974b7144e263cd94815b5676e0f40bc62487f5411b5bc38a8bc41d0511' 
  AND token = 'u0INARwN3rNW7gNDfspIcY1A8fzBj7CGBmXf+8AzRwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}