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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '336e0eead7b62c29f24bebb97cfa5d5798050ce059c747deb4f5aa14e4a2eb04' 
  AND token = 'cT/CxilrZyY29rbFbmrOh9yK/737xPIFjZ4ZqBU32qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}