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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '78b623348039b02df7df112eba3034b8fba9d7a257e394fd9c66154c9c1fc750' 
  AND token = '8seoZSWUJrNxgfeY2PR5txD8kY6u7FM3OS/SbI/gi38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}