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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a244bbfc0c3516c2c78900e92f4631b152ee3b7155ecb4846365e1c6b344e346' 
  AND token = 'RmNhMYxXAfoEhbJL9iRh1jcUhfx+WATVht+dkOYi4Rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}