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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3609979a4bce04cbc66a282f6fa0897053d3bd3b8d419dc14998e546f7d66f43' 
  AND token = 'n9qxrSL1kXyOC2Lc6tN7OAV8mM4AJ2Tm92nEhIuhh+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}