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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49697d1c73c59bcd842c5bbabdf7aeb958da719ee07d182fdf674b493ad3c4f1' 
  AND token = 'JoSIbQdoes46MMF+2Ebl65WUJYucadUGJhYDx7mI8/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}