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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5065efc1bad964afc3c013f2b4b01c6ee08ce49af534c7759a4ef5301da9ad97' 
  AND token = '+HWD835xnODj7Ad6UgEfK8t2hTcn3lGALdW44iarQWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}