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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e8bda822641f195410c69a62498ad8dcfdfba3bf615c7dc5e62cc5503af95e01' 
  AND token = 'QNPFyXO1QNZ+MryHAV0k2SNyBDuRnfGM0hiFuT7gSZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}