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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4441667ba0f49531f7915257cfa49c8540337905ee1ea82513abca1552f54139' 
  AND token = 'inFTRTKHj/ryEY9kZqK+f6TxCyZYOAN1CE1rqxJirpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}