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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ad394ba4bfda7321e7f6ee05bb3a8b09c436a09546bc6956021412e612d2a4b8' 
  AND token = 'ph3KQwhJ0FI1ISJGkReUufETryv6euOv2vRsdzIjKbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}