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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2b00e3ce5c71387ce712f8100f6a26e7c3f5605dc6921b216c9c1adadec05820' 
  AND token = 'Zzhj8v/tzMJIisMMwuzfo1/McTu9G7lxZAtRc3b8oCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}