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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7946c3e6e3a6016bb6a4d4ab2f67157dc63dbccda936aaa360e37f6eb98f8096' 
  AND token = 'I2O6h4xycAYK0/go3uXjrqr5GQWfKXL2GFgYkbLeU5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}