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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '51ab473a027ff25280165d1fb4a8788a4b78efaf2f268617eb8b6823921c9602' 
  AND token = 'yZ0whSakXnQHyaN0osI30XSbW3MYWNRUUz7Yv+zyVtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}