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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '53ca2eb3e5c5f9866c56429afc5a437c1b3b4b8999b0cb40e420fc4832554da2' 
  AND token = 'w++bryRKNmgsChYaot4brhT7SBa3/W44KMYeBqC2OUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}