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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '60787b0901efd968efb9fd67c4cedf900de0c19f6eef0a085cf93f021ac4341c' 
  AND token = 'mb50umRUueLxPY9oJz4OB+24efxMD1zgAKs4kqmgF7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}