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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'df21c038eaf053279bb7d95f43a95b9590fb81132e08076a73dede0557f3f24a' 
  AND token = 'aoU8DR0ZlDRg7EUf3PspGRtAD2UHIWlN39S0JSlI29Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}