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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49811dcd13ee11595e129c386b32d09874a33f5108e558c3973702a9d0dcf127' 
  AND token = 'qdoRonchtvW4pv593+vTmPJj0dNlR2ExxoQtcxxmrEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}