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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b46201b6281cdb3021601da17c0667aafc12c2aabe11ac111600c0d2418bf249' 
  AND token = 'Fu/UQFqshd0H1XUlPPfSVuuG5cbCDqaXeTwqEl2dyFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}