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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4963456e50f89e2e06e234b1b5ac17d85d20f1f16529566ebdc42b4280343353' 
  AND token = 'yMfhDOFtLr9WWsk9BrjFnZtS2N4tlToZ4/jDxwfnH80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}