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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '375ff7cfcc043137fcb04b2931ee3d41475beae3d7b242a540f6b7c2ca20cf18' 
  AND token = 'm/M9WEiJ9DbeYE3/27EXSOobEb2lSAd/16L2y5AsAHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}