SELECT 
  1 
FROM 
  cscart_aprilec_print_temp_designs 
WHERE 
  session_id = '34OJ-1DWQ-6TRX-UHHE-HZLC-PIVG-ZC8N-125A' 
  AND product_id = 284 
  AND expires_at > 1778128595 
  AND confirmed = 'Y' 
LIMIT 
  1

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}