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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '25314b797d08b366441a54aaf391de8ed5e2b15f60662685907665f1f23943a5' 
  AND token = 'xD8C1F/L3echPjhDwFllhnEhbJcXxXNEfyL9OpDzn2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}