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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '381526741fe52c7391d12256becf04e42f51336c4e35f63e8043f1c65591e756' 
  AND token = 'bw2NwNhCfB8s7sp/fjHg9TDqsQI3d+LpjbljJnDjEfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}