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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '538ddb1be795c06b45eb67476ba4de9c409aa73a7abf2a3229b0fead505a97e8' 
  AND token = 'UB1e0WnUhXdTz3shRaukqGF5amTddhsjNRCDJ+Yzw1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}