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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2c6a3dc4d07e9fddcebad00e1f8a67179fa82f33e3b418107e10a677116ebf65' 
  AND token = 'nmALs7De3WiqNlQvoO1E1mGUvhvh/FZdtQleCnLhq/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}