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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '53f7482d42fc730a256ad19b9835642e28e8fb0bb40f947ba95f575b0a44623a' 
  AND token = '2G7OiT0P1g75mzkKEDtEHYb61vkjrEaHZYXHMwI0K4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}