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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3d49b2aa474f29ce1a292abf46f890ca0c54f16dabdb91157d3e143e7a42894b' 
  AND token = 'YXL2JOLc7CMZVrVv09zmY1egLODRbsaZRtuAKzMOUAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}