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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'dd85594d8c7d58c1afe4ef6256c91179a427a29e01deaab990eecddab21e5eb1' 
  AND token = 'U3D2m/OfHsdNFt/FI8a5JoFcoK/M7fCPXaqTm6GdU/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}