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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b0defea994aa0639a59385e503fe5a62c649e03095085ad2fb193c60aff6e22e' 
  AND token = '012OxSFOWSoCkcfo6+X3UKiC/fPR0BgY5BtudwKtHKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}