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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e5ff2aecc508e76d97233f65c788fdd43d44addbb4a5790d75635a6b2bac70fd' 
  AND token = 'ns+jE5U5tql+v3BZDPT82bOKSejzyKd4SvXeKsBegrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}