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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0721d40db4bf4094b476b10ec47822087cc42f3ac28c507d478ab25b2462c126' 
  AND token = 'm5MGjTcprYHaCJz+YbGN/WcIo0G8IPRduteHPYGcf/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}