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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '37f5840744b941c4957e8dc40970b4d3cc7abe222f2a19a18348a76544c01c02' 
  AND token = 'QeUzuUL9FLo6o55fVkfazJlA9xPe5qDKZsCHmO3/K7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}