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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0e7f2725eb8bc82aff192c0737952990634ef8f55b72176dbccc9db74efc64a9' 
  AND token = 'p5eR4CILFYxfLmw26b/Y7xdEuGoaFR2hgjxUpLJfa5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}