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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '98849eaf9b3d36ea85dc1eb53e45beb6052236d41bc963b6cc3657266e4f162d' 
  AND token = 'BlkvZ1kj+0wzouTTmTDbd7AD+S9y60TlHMAzoLQnvTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}