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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9b728640e2a484fd3e49de1bf9408004bb4ceabb2848ee6147a5e44d994b0d6c' 
  AND token = 'Yga+OtDRsySvFU0Jz2Y5gxiNatkL/b3g3WkE4CC99qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}