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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6b86d88e880e7ebf3ecb974df4d3ce2a7278483d320a58e2cf612df4cacec351' 
  AND token = 'WHqIYzI1M5ePdjk0GxPwHSMmXCY2qlzzKYfDT3SHbSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}