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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c8cf8c8858bf82447516526cec59a10d1a447003e525bc7baf2f6fc2031efe95' 
  AND token = 'GGNYa1PwN4jlZnlqnl/MOefzrxk0rt2elZQkQ8KVkIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}