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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2ba87065d70a8f02d5970263b8cff26b84678df185ae2f1c3d05f2be2cd3a526' 
  AND token = 'vWTaPGNNAPP5ILTtjaSxzbKFazAQDjLnsdVW1uBPQK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}