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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '46142c6e03e21487c54b4ba86820e115b1a74200b134526f2565f609f67f7daa' 
  AND token = 'WYmXlP5UOpNlkh9sX65Z9MfIdfU/yT9zeVXsr+0SusM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}