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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9f121bd6b734a804d2fd79086d637ee9cfbf3ab87654810e714cca62e95a30e6' 
  AND token = 'E5MmLedjGMc4MSsRAROKtXU/P3FgtpiWR7uNfOuLuwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}