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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '46a8364132fbc89a7dad58a3deac9e6ba3bac45edcde263e0c14fdad795a2c37' 
  AND token = 'wUxp1R1a1UznyrQWiCoYZL6/t8fMLCwL1tkYo9sG780=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}