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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'eb8048b9713362108772f64baf4348643cec50ef23b8e24e4ca12262a19e7441' 
  AND token = '6Dv0zMr4U1FyLd82CkgvIIbedA4989TW9ltU22hL8OQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}