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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '291b51a7960755a9fdbf6423196eaee7a211a371431aba7492e2dcae070f98bb' 
  AND token = 'nxcuHtYN5ydDw8cAcSEbqGI08zQYj78/6uwQUvegTPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}