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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '423c543bcfaf7f567602171c1dcc4506e65d82c6b6df3aad382fefb45a483aad' 
  AND token = 'AD6/qN/r0E1t8tp1TVf3rGgPvKDe8PtP+kx2TXYO+sk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}