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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '12cd827bcb0832b82f896cf0c17c5d39036e84414db471ecc6639dbccf04e8ed' 
  AND token = 'ckO66Bq8b2OlztS/4012MGTiUiGV+wNmAD+nyuP2qsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}