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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2e04436ad3b6ceab0e4b842743c824c4ec66c27cfbd92c1b38e25e6f2e81a552' 
  AND token = 'trcfs1mTcX+Am/g+cz0PU8v8tSgK32FX/QWD/RxX7Fc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}