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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6bfa22f1c6b3273df40fbb7c3f9d90b1e5db31207a43951715ad8a7d829d74ba' 
  AND token = '2XPF53mfM2k7xdEr2m0ONxMGFxviQhjp1k9b55N8aCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}