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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49c27877e0fa6841429abdcb6d266a41a18743cc82bb64684aa7124b0c26a95b' 
  AND token = 'AZAFum/oJ6Qfa8n5HvAC4gGJFSnLCeGaK67ESanjG1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}