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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '64f9d3ba2c983bb47313666202cb2c77e7e586797a0b33b78ae904878e353eef' 
  AND token = 'chWeLPO2C29Lqi1GGPqt7iDFr6Seb929csA1sf2IrJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}